DNA-PK-IN-10_product_DataBase

CAS: 2919315-89-0 F: C25H28N6O2 W: 444.53

DNA-PK-IN-10 is a DNA-PK inhibitor. DNA-PK-IN-10 can be used for the research of breast cancer and non-small cell lung c

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	DNA-PK-IN-10 is a DNA-PK inhibitor. DNA-PK-IN-10 can be used for the research of breast cancer and non-small cell lung cancer[1].
Invitro	DNA-PK-IN-10 (Example 31) 抑制 MDA-MB-468 细胞的活力，IC50 值为 11.2 nM[1]。
In Vivo	DNA-PK-IN-10 (Example 31) (30mg/kg；每天给药两次) 显着抑制肿瘤生长，并且在接种 NCI-H1703 细胞的小鼠中表现出良好的耐受性[1]。
Name	DNA-PK-IN-10
CAS	2919315-89-0
Formula	C25H28N6O2
Molar Mass	444.53
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Kuncheng C, et, al. Dna-pk selective inhibitor, and preparation method therefor and use thereof. WO2023036156A1.

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