| Bioactivity | DNA Gyrase/DHFR-IN-1 is a dual inhibitor of bacterial DNA gyrase and DHFR, with IC50s of 182 μM and 3.90 μM for E. coli DNA gyrase and DHFR respectively. DNA Gyrase/DHFR-IN-1 has bactericidal and antifungal activity[1]. |
| Invitro | DNA Gyrase/DHFR-IN-1 的 MIC 值为 16 nM（枯草芽孢杆菌）、24 nM（金黄色葡萄球菌）、51 nM（大肠杆菌）、53 nM（铜绿假单胞菌）、15.50 μM（黄曲霉）和 19.50 μM（白色念珠菌）[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> DNA Gyrase/DHFR-IN-1 相关抗体: |
| Formula | C25H20N4O |
| Molar Mass | 392.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lamya H. Al-Wahaibi, et al. Synthesis and Antimicrobial Evaluation of New 1,2,4-Triazolo[1,5-a]pyrimidine-Based Derivatives as Dual Inhibitors of Bacterial DNA Gyrase and DHFR. |