| Bioactivity | DNA Gyrase-IN-8 is a potent DNA gyrase inhibitor with an IC50 value of 8.45 µM. DNA Gyrase-IN-8 shows antimicrobial activity[1]. |
| Target | IC50: 8.45 µM (DNA gyrase) |
| Invitro | DNA Gyrase-IN-8 (compound 10) 显示出抗菌活性，对 S. aureus (ATCC 6538-P)，C. albicans (ATTC 10231) 的 MIC 值分别为 191.36、191.36 µM[1]。 |
| Name | DNA Gyrase-IN-8 |
| Formula | C19H14BrN5O |
| Molar Mass | 408.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Abd El-Lateef HM, et al. Design and Synthesis of 2-(4-Bromophenyl)Quinoline-4-Carbohydrazide Derivatives via Molecular Hybridization as Novel Microbial DNA-Gyrase Inhibitors. ACS Omega. 2023 May 11;8(20):17948-17965. |