| Bioactivity | DMU-212 is a methylated derivative of Resveratrol (HY-16561), with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. DMU-212 induces mitotic arrest via induction of apoptosis and activation of ERK1/2 protein. DMU-212 has orally active[1][2]. | ||||||||||||
| Invitro | DMU-212 (0.3125-40 μM) inhibits growth of A375, MeWo, Bro and M5 human melanoma cells[1].DMU-212 (30-50 μM; 24 hours) induces upregulation of cell cycle inhibitors, apoptosis and ERK activation in A375 cells[1]. Cell Proliferation Assay[1] Cell Line: | ||||||||||||
| Name | DMU-212 | ||||||||||||
| CAS | 134029-62-2 | ||||||||||||
| Formula | C18H20O4 | ||||||||||||
| Molar Mass | 300.35 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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