| Bioactivity | DMT1 blocker 1 (compound 6f) is a blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0.64 μM, is expected to block iron uptake by enterocytes in vivo[1]. | ||||||||||||
| Target | IC50: 0.64 μM (DMT1 blocker 1) | ||||||||||||
| Name | DMT1 blocker 1 | ||||||||||||
| CAS | 1354790-56-9 | ||||||||||||
| Formula | C16H14N4O2 | ||||||||||||
| Molar Mass | 294.31 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Cadieux JA, et al. Synthesis and biological evaluation of substituted pyrazoles as blockers of divalent metal transporter 1 (DMT1). Bioorg Med Chem Lett. 2012 Jan 1;22(1):90-5. |
DMT1 blocker 1
CAS: 1354790-56-9 F: C16H14N4O2 W: 294.31
DMT1 blocker 1 (compound 6f) is a blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0.64 μM, is expected t
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