| Bioactivity | DMANI is an intramolecular charge transfer (ICT)-based mitochondria-targeted ratiometric fluorescent probe. DMANI can monitor mitochondrial peroxynitrite (ONOO−) in living cells[1]. |
| Invitro | 在 PBS 缓冲液（10 mM，pH = 7.4）中，DMANI（5 μM）在 525 和 346 nm 处显示吸收带，但添加 30 μM ONOO− 后，吸收明显降低，同时在约 360 nm 处出现新峰。在发射光谱中，在 692 nm 处观察到荧光明显降低，在 DMANI 与 ONOO− 的情况下，在 444 nm 处出现新的发射带并迅速增加[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> DMANI 相关抗体: |
| CAS | 2978635-30-0 |
| Formula | C25H27IN2 |
| Molar Mass | 482.40 |
| Appearance | 固体 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Yuting Du, et al. ICT-based fluorescent ratiometric probe for monitoring mitochondrial peroxynitrite in living cells. New J. Chem., 2021,45, 12915-12921. |