| Bioactivity | DM3-SMe is a maytansine derivative and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs), which can be linked to antibody through disulfide bond or stable thioether bond. DM3-SMe shows highly cytotoxic activity in vitro with an IC50 of 0.0011 nM[1][2]. |
| Name | DM3-SMe |
| CAS | 796073-70-6 |
| Formula | C38H54ClN3O10S2 |
| Molar Mass | 812.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
DM3-SMe
CAS: 796073-70-6 F: C38H54ClN3O10S2 W: 812.43
DM3-SMe is a maytansine derivative and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs)
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