| Bioactivity | DM1-SMe is an unconjugated form of the Maytansinoid in IMGN901. DM1-SMe is about 3-10-fold more potent than the parent drug Maytansine, with IC50s ranging from 0.003 to 0.01 nM for DM1-SMe in a panel of human tumor cell lines[1]. |
| Name | DM1-SMe |
| CAS | 138148-68-2 |
| Formula | C36H50ClN3O10S2 |
| Molar Mass | 784.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
DM1-SMe
CAS: 138148-68-2 F: C36H50ClN3O10S2 W: 784.38
DM1-SMe is an unconjugated form of the Maytansinoid in IMGN901. DM1-SMe is about 3-10-fold more potent than the parent d
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