DM-CO-(CH2)5-SMe_product_DataBase

CAS: 2243689-84-9 F: C39H56ClN3O10S W: 794.39

DM-CO-(CH2)5-SMe is an anticancer agent derived from antibody-drug conjugates (ADC) metabolite with cytotoxicity to H170

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	DM-CO-(CH2)5-SMe is an anticancer agent derived from antibody-drug conjugates (ADC) metabolite with cytotoxicity to H1703, H1975, COLO704 and Colo720E cells[1].
Invitro	DM-CO-(CH2)5-SMe (Compound 25 a) (0.00008-30 nM；5 d) 抑制 H1703、H1975 和 COLO704 细胞的活性，IC50 值分别为 2.27 pM、0.893 pM 和 3.04 pM[1]。DM-CO-(CH2)5-SMe 抑制 Colo720E 细胞的活性，IC50 值为 3 pM[1]。
Name	DM-CO-(CH2)5-SMe
CAS	2243689-84-9
Formula	C39H56ClN3O10S
Molar Mass	794.39
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Widdison, et al. Preparation of maytansinoid derivatives with self-immolative peptide linkers and their conjugates as antitumor agents. World Intellectual Property Organization. WO2018160539.

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