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DL-Methionine-d4

CAS: 93709-61-6 F: C5H7D4NO2S W: 153.24

DL-Methionine-d4 is the deuterium labeled DL-Methionine. DL-Methionine is an essential amino acid containing sulfur with
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Bioactivity DL-Methionine-d4 is the deuterium labeled DL-Methionine. DL-Methionine is an essential amino acid containing sulfur with oxidative stress defense effects. DL-Methionine can be used for animal natural feed. DL-Methionine also kills H. rostochiensis on potato plants[1][2][3].
Invitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Name DL-Methionine-d4
CAS 93709-61-6
Formula C5H7D4NO2S
Molar Mass 153.24
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. K. evans, et al. Effects of amino acids on the reproduction of Heterodera rostochiensis. Nematologica, 1971, 17(4), 495-500. [3]. Swennen Q, et al. Effects of dietary protein content and 2-hydroxy-4-methylthiobutanoic acid or DL-methionine supplementation on performance and oxidative status of broiler chickens. Br J Nutr. 2011 Dec;106(12):1845-54. [4]. Garlich JD. Response of broilers to DL-methionine hydroxy analog free acid, DL-methionine, and L-methionine. Poult Sci. 1985 Aug;64(8):1541-8.