| Bioactivity | DL-Acetylshikonin is a non-selective, reversible cytochrome P450 inhibitor with IC50 values of 1.4-4.0 μM. DL-Acetylshikonin has anti-cancer and anti-inflammatory activities[1]. |
| Invitro | DL-Acetylshikonin 抑制 CYP3A 介导的睾酮 (testosterone) 和 Nifedipine (HY-B0284) 代谢，IC50 值分别为 5.2 μM 和 3.0 μM，表明其以不依赖底物的方式抑制 CYP3A 活性[1]。DL-Acetylshikonin 不是一种时间依赖性抑制剂[1]。 |
| Name | DL-Acetylshikonin |
| CAS | 54984-93-9 |
| Formula | C18H18O6 |
| Molar Mass | 330.33 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shon JC, et al. Acetylshikonin is a novel non-selective cytochrome P450 inhibitor. Biopharm Drug Dispos. 2017 Dec;38(9):553-556. |
DL-Acetylshikonin
CAS: 54984-93-9 F: C18H18O6 W: 330.33
DL-Acetylshikonin is a non-selective, reversible cytochrome P450 inhibitor with IC50 values of 1.4-4.0 μM. DL-Acetylshi
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