Bioactivity | DL-AP7 is a competitive NMDA antagonist and an anticonvulsant. DL-AP7 blocks the NMDA-induced convulsions and impairs learning performance in a passive avoidance task in mice[1]. |
In Vivo | DL-AP7 (ICV) blocks the NMDA-induced convulsions (ED50=0.22 nmol/mouse) and impairs learning performance in a passive avoidance task in mice[1]. |
Name | DL-AP7 |
CAS | 85797-13-3 |
Formula | C7H16NO5P |
Molar Mass | 225.18 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Chiamulera C, et al. Effect of NMDA- and strychnine-insensitive glycine site antagonists on NMDA-mediated convulsions and learning. Psychopharmacology (Berl). 1990;102(4):551-552. |