Bioactivity | DK2403 (compound 25) is a MAP2K7 inhibitor (IC50=0.01 μM). DK2403 can effectively inhibit MAP2K7 without significantly disrupting the larger kinase group and can be used to study childhood T-cell acute lymphoblastic leukemia[1]. |
CAS | 2902651-64-1 |
Formula | C19H17ClN4O2 |
Molar Mass | 368.82 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kim DR, et al. Rational Design of Highly Potent and Selective Covalent MAP2K7 Inhibitors. ACS Med Chem Lett. 2023 Apr 17;14(5):606-613. |