| Bioactivity | DH-376 is a potent diacylglycerol lipase inhibitor with pIC50 values of 8.6 and 8.9 for ABHD6 and DAGLα, respectively. DH-376 prevents fasting-induced refeeding of mice[1]. |
| In Vivo | DH-376 (50 mg/kg; i.p.) 减少小鼠禁食诱导的再喂食[1]。 Animal Model: |
| Name | DH-376 |
| CAS | 1848233-57-7 |
| Formula | C31H28F2N4O3 |
| Molar Mass | 542.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Deng H, et, al. Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding. J Med Chem. 2017 Jan 12;60(1):428-440. |