Bioactivity | DGKα&ζ-IN-1 (Compound II) is a DGK target inhibitor. DGKα&ζ-IN-1 can enhance the function of T cells, and has a synergistic effect with PD-1, which has therapeutic effects IN both immune and tumor[1]. |
Name | DGKα&ζ-IN-1 |
CAS | 2830643-06-4 |
Formula | C29H31FN8O2 |
Molar Mass | 542.61 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Tu-Sekine B, et al. DGK-θ: Structure, Enzymology, and Physiological Roles. Front Cell Dev Biol. 2016 Sep 14;4:101. |