| Bioactivity | DENV-IN-7, a flavone analog, is a dengue virus (DENV) inhibitor with an EC50 value of 70 nM. DENV-IN-7 has low toxicity against normal cell and anti-dengue activity[1]. |
| Invitro | DENV-IN-7 (compound 5d; 10 μM; 48 h) 对 LLC/MK2 细胞具有低毒性[1]。DENV-IN-7 (1 nM-10 μM; 72 h) 具有抗登革热活性，并抑制 DENV2 感染的 LLC/MK2 细胞中的病毒复制[1]。 Cell Viability Assay[1] Cell Line: |
| Name | DENV-IN-7 |
| CAS | 2499537-22-1 |
| Formula | C24H22O8 |
| Molar Mass | 438.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Patigo A, et, al. Design, synthesis, in vitro, in silico, and SAR studies of flavone analogs towards anti-dengue activity. Sci Rep. 2022 Dec 14;12(1):21646. |