| Bioactivity | DDO-02005 (free base) is a potent Kv1.5 potassium channel inhibitor with an IC50 value of 0.72 μM. DDO-02005 (free base) has good anti-atrial fibrillation (AF) effect in CaCl2-ACh AF rats model and effective anti-arrhythmic activity caused by aconitine[1]. |
| Target | IC50: 0.72 μM (Kv1.5 potassium channel) |
| Name | DDO-02005 free base |
| CAS | 1186134-30-4 |
| Formula | C21H25N3O2 |
| Molar Mass | 351.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhao L, et al. Design, synthesis, and biological evaluation of arylmethylpiperidines as Kv1.5 potassium channel inhibitors. J Enzyme Inhib Med Chem. 2022;37(1):462-471. |
DDO-02005 free base
CAS: 1186134-30-4 F: C21H25N3O2 W: 351.44
DDO-02005 (free base) is a potent Kv1.5 potassium channel inhibitor with an IC50 value of 0.72 μM. DDO-02005 (free bas
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