PeptideDB

DCOIT

CAS: 64359-81-5 F: C11H17Cl2NOS W: 282.23

DCOIT is a representative isothiazolinone that stimulates the gonadotropin-releasing hormone receptor (GnRHR)-mediated s
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity DCOIT is a representative isothiazolinone that stimulates the gonadotropin-releasing hormone receptor (GnRHR)-mediated synthesis of follicle-stimulating hormone and luteinizing hormone in the brain. DCOIT interferes with G protein-coupled receptors, MAPK and Ca2+ signaling cascades[1].
Name DCOIT
CAS 64359-81-5
Formula C11H17Cl2NOS
Molar Mass 282.23
Appearance 固体
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Tang L, et al. Isothiazolinone Disrupts Reproductive Endocrinology by Targeting the G-Protein-Coupled Receptor Signaling. Environ Sci Technol. 2024 Jan 3.