| Bioactivity | DCN-83, an anti-leishmania agent, is most potent against the amastigote form with an IC50 of 0.71 μM. DCN-83 has the potential to cross the blood-brain barrier and central nervous system[1]. |
| Invitro | DCN-83 没有 AMES 毒性和肝毒性[1]。DCN-83 对巨噬细胞 J774.A1 具有轻微的抑制作用，CC50 值为 84.73 μM[1]。 |
| Name | DCN-83 |
| Formula | C20H18BrN3S |
| Molar Mass | 412.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Luna IS, et al. Computer-Aided drug design of new 2-amino-thiophene derivatives as anti-leishmanial agents. Eur J Med Chem. 2023 Mar 15;250:115223. |