| Bioactivity | DBMB is an inhibitor of spleen tyrosine kinase (Syk), capable of significantly inhibiting the activity of Syk kinase. DBMB exhibits anti-inflammatory activity by suppressing the signaling of NF-κB, which in turn reduces the production of inflammatory mediators such as nitric oxide (NO) and prostaglandin E2 (PGE2). DBMB can be utilized in research on inflammatory diseases[1]. |
| CAS | 314027-66-2 |
| Formula | C24H22N4O |
| Molar Mass | 382.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kim E, et al. 1-(2, 3-dibenzimidazol-2-ylpropyl)-2-methoxybenzene is a Syk inhibitor with anti-inflammatory properties[J]. Molecules, 2016, 21(4): 508. |