| Bioactivity | DBCO-C3-amide-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-C3-amide-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups[1]. |
| Formula | C39H49N3O12 |
| Molar Mass | 751.82 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zimmerman ES, et al. Production of site-specific antibody-drug conjugates using optimized non-natural amino acids in a cell-free expression system. Bioconjug Chem. 2014 Feb 19;25(2):351-61. |
DBCO-C3-amide-PEG6-NHS ester
CAS: F: C39H49N3O12 W: 751.82
DBCO-C3-amide-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with prim
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