| Bioactivity | DB18 is a potent and selective inhibitor of CDC2-like kinases (CLKs), with IC50 values in the range of 10-30 nM for CLK1, CLK2 and CLK4. DB18 has anti-tumor activity[1]. |
| Name | DB18 |
| CAS | 2587177-94-2 |
| Formula | C24H18ClN7O3 |
| Molar Mass | 487.90 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Brahmaiah D, et al. Discovery of DB18, a potent inhibitor of CLK kinases with a high selectivity against DYRK1A kinase. Bioorg Med Chem. 2021 Feb 1;31:115962. |
DB18
CAS: 2587177-94-2 F: C24H18ClN7O3 W: 487.90
DB18 is a potent and selective inhibitor of CDC2-like kinases (CLKs), with IC50 values in the range of 10-30 nM for CLK1
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.