| Bioactivity | DAPT (GSI-IX) (GMP) is DAPT (HY-13027) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DAPT is a potent and orally active γ-secretase inhibitor[1][2]. |
| Invitro | DAPT (GMP) (9 d) induces human induced pluripotent stem cells develop into expandable myoblasts[1].DAPT (GMP) (13 d) induces human pluripotent stem cells (hPSCs) develop into functional neurons[2]. |
| Name | DAPT (GMP) |
| CAS | 208255-80-5 |
| Formula | C23H26F2N2O4 |
| Molar Mass | 432.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Choi IY, et al. Concordant but Varied Phenotypes among Duchenne Muscular Dystrophy Patient-Specific Myoblasts Derived using a Human iPSC-Based Model. Cell Rep. 2016 Jun 7;15(10):2301-2312. [2]. Qi Y, et al. Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells. Nat Biotechnol. 2017 Feb;35(2):154-163. |
DAPT (GMP)
CAS: 208255-80-5 F: C23H26F2N2O4 W: 432.46
DAPT (GSI-IX) (GMP)is DAPT (HY-13027) produced by using GMP guidelines. GMP small molecules works appropriately as an au
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