| Bioactivity | DAPM is a Notch pathway inhibitor with anticancer activity and antiproliferative effects. DAPM effectively inhibits tubular adenoma development by inhibiting cell proliferation and inducing the expression of Krüppel-like factor 4 (KLF4) and p21 in human colon cancer cells[1]. |
| Name | DAPM |
| CAS | 208255-51-0 |
| Sequence | N-[N-3,5-Difluorophenacetyl]-L-alanyl-S-phenylglycine methyl ester |
| Formula | C20H20F2N2O4 |
| Molar Mass | 390.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Miyamoto S, et al. Suppression of colon carcinogenesis by targeting Notch signaling. Carcinogenesis. 2013 Oct;34(10):2415-23. |