Bioactivity | DANP dihydrochloride is a bulge base recognition probe that strongly and specifically binds to the single cytosine and thymine bulges. DANP dihydrochloride could stabilize not only a single cytosine but also the thymine bulge in duplex DNA[1]. |
Formula | C14H24Cl2N6 |
Molar Mass | 347.29 |
Appearance | 固体 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
Reference | [1]. Suda H, et al. N,N'-Bis(3-aminopropyl)-2,7-diamino-1,8-naphthyridine stabilized a single pyrimidine bulge in duplex DNA. Bioorg Med Chem. 2005 Jul 15;13(14):4507-12. |