| Bioactivity | DAG peptide is a cyclic peptide. DAG peptide selectively recognizes a subset of astrocytes that are activated in Alzheimer's disease (AD) starting at an early stage of the disease. DAG peptide can be used as a tool to enhance the delivery of therapeutics and imaging agents to sites of vascular changes and astrogliosis in diseases associated with neuroinflammation[1]. |
| Sequence | Cys-Asp-Ala-Gly-Arg-Lys-Gln-Lys-Cys (disulfide bridge: Cys1-Cys9) |
| Shortening | CDAGRKQKC (disulfide bridge: Cys1-Cys9) |
| Formula | C38H67N15O13S2 |
| Molar Mass | 1006.16 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mann AP, et al. Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer's disease. Nat Commun. 2017 Nov 10;8(1):1403. |