| Bioactivity | D75-4590, a pyridobenzimidazole derivative and a β-1,6-glucan synthesis inhibitor, possesses antifungal activity[1]. | ||||||||||||
| Invitro | D75-4590 has activities against a variety of Candida species, including fluconazole-resistant strains. Most strains of C. albicans, C. tropicalis, and C. parapsilosis displayed trailing growth phenomena similar to those observed in the presence of azoles[1]. | ||||||||||||
| Name | D75-4590 | ||||||||||||
| CAS | 384376-42-5 | ||||||||||||
| Formula | C21H27N5 | ||||||||||||
| Molar Mass | 349.47 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Akihiro Kitamura, et al. Discovery of a small-molecule inhibitor of {beta}-1,6-glucan synthesis. Antimicrob Agents Chemother. 2009 Feb;53(2):670-7. |