| Bioactivity | D1R antagonist 2 (compound 23b) is a potent and selective ligand of dopamine receptor D3R, containing a THPB template. D1R antagonist 2 is also an antagonist for both G-protein- and β-arrestin-based signaling[1]. |
| Target | D3R |
| Name | D1R antagonist 2 |
| Formula | C27H37NO5 |
| Molar Mass | 455.59 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Namballa HK, et al. Discovery of Selective Dopamine Receptor Ligands Derived from (-)-Stepholidine via C-3 Alkoxylation and C-3/C-9 Dialkoxylation. J Med Chem. 2023 Jul 8. |