Bioactivity | D-F07 is a prodrug with an aldehyde shielding group and an IRE-1 inhibitor that induces apoptosis (Apoptosis). D-F07 has antitumor activity[1][2]. |
CAS | 2361297-58-5 |
Formula | C18H21NO6 |
Molar Mass | 347.36 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Shao A, et al. Development of Tumor-Targeting IRE-1 Inhibitors for B-cell Cancer Therapy. Mol Cancer Ther. 2020 Dec;19(12):2432-2444. [2]. Shao A, et al. IRE-1-Targeting Caged Prodrug with Endoplasmic Reticulum Stress-Inducing and XBP-1S-Inhibiting Activities for Cancer Therapy. Mol Pharm. 2022 Apr 4;19(4):1059-1067. |