| Bioactivity | D-87503 is a potent inhibitor of PI3k/Akt/mTOR, with the IC50s of 62 nM and 0.76 μM, respectively for PI3k and Erk2. D-87503 effectively suppressed the target downstream substrates Akt and Rsk1 kinase of the PI3k/Akt/mTOR signaling pathway[1]. |
| CAS | 800394-83-6 |
| Formula | C17H15N5OS |
| Molar Mass | 337.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mukesh Chandra Joshi, et al. Potent Phosphatidylinositol 3-Kinase Inhibitors and Their Biology. Review Curr Drug Discov Technol. 2014 Jun;11(2):113-26. |