| Bioactivity | Cytogenin (Antibiotic MI 43-37F11) is an orally active antineoplastic antibiotic. Cytogenin regulates the inflammatory cytokine, reduces the levels of iNOS, NO and IL-6 in mouse macrophages, and exhibits antidiabetic efficacy in mice. Cytogenin inhibits growth of Ehrlich ascites tumor in mouse model[1][2][3]. |
| CAS | 132971-59-6 |
| Formula | C11H10O5 |
| Molar Mass | 222.19 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kumagai H, et al., Biosynthesis of antitumor antibiotic, cytogenin. J Antibiot (Tokyo). 1994 Apr;47(4):440-6. [2]. Kumagai H, et al., Cytogenin, a novel antitumor substance. J Antibiot (Tokyo). 1990 Nov;43(11):1505-7. [3]. Kumagai H, et al., Effect of cytogenin, a novel immunomodulator, on streptozotocin-induced diabetes in mice. J Antibiot (Tokyo). 2005 Mar;58(3):202-5. |