Bioactivity | Cytochalasin E, an epoxide containing Aspergillus-derived fungal metabolite, inhibits angiogenesis and tumor growth. Cytochalasin E is a potent actin depolymerization agent, and it binds and caps the barbed end of actin filaments to prevent actin elongation[1][2]. |
Invitro | Cytochalasin E prominently inhibits the growth of A549 cells in a dose-dependent manner[3].Cytochalasin E could induce the up-regulation of autophagy-related protein (LC3-II) and SQSTM1/p62[3]. |
Name | Cytochalasin E |
CAS | 36011-19-5 |
Formula | C28H33NO7 |
Molar Mass | 495.56 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |