| Bioactivity | Cytisinicline (Cytisine) is an alkaloid. Cytisinicline (Cytisine) is a partial agonist of α4β2 nAChRs[1], and partial to full agonist at β4 containing receptors and α7 receptors[2]. Has been used medically to help with smoking cessation[3]. | ||||||||||||
| Invitro | Cytisinicline (Cytisine) (2.5, 5 and 10 mM) is capable of inducing apoptosis in HepG2 cells[4].Treatment with Cytisinicline (Cytisine) increases the percentage of cells in the sub-G1 phase (P<0.01). The preincubation of HepG2 cells with Cytisinicline (Cytisine) (2.5, 5 and 10 mM) significantly increases the sub-G1 cell population[4]. | ||||||||||||
| Name | Cytisinicline | ||||||||||||
| CAS | 485-35-8 | ||||||||||||
| Formula | C11H14N2O | ||||||||||||
| Molar Mass | 190.24 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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