| Bioactivity | CysOx2 is a reaction-based fluorogenic probe for sulfenic acid (Ex/Em: 394/535 nm). CysOx2 can be used for detecting protein cysteine oxidation in living cells[1]. |
| Target | Sulfenic acid |
| Invitro | CysOx2 (1 mM; 1 h) reacts with H2O2 and produces fluorescence in 50 mM HEPES pH 7.4[1].CysOx2 is cell permeable[1].CysOx2 (50 μM; 1 h) shows fluorescence signal in epitope-tagged wild-type EGFR expression HeLa cells, the signal is absent in C797S EGFR expression HeLa cells[1]. |
| Name | CysOx2 |
| Formula | C15H12FNO3S |
| Molar Mass | 305.32 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ferreira RB, et al. Reaction-based fluorogenic probes for detecting protein cysteine oxidation in living cells. Nat Commun. 2022 Sep 21;13(1):5522. |