| Bioactivity | Cyclotraxin B TFA, a cyclic peptide, is a highly potent and selective TrkB inhibitor without altering the binding of BDNF. Cyclotraxin B TFA non-competitively inhibits BDNF-induced TrkB activity with an IC50 of 0.30 nM. Cyclotraxin B TFA can crosse the blood-brain-barrier and has analgesic and anxiolytic-like behavioral effects[1][2][3]. |
| Name | Cyclotraxin B TFA |
| Shortening | CNPMGYTKEGC (Disulfide bridge:Cys1-Cys11) |
| Formula | C50H74F3N13O19S3 |
| Molar Mass | 1314.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Cyclotraxin B TFA
CAS: F: C50H74F3N13O19S3 W: 1314.39
Cyclotraxin B TFA, a cyclic peptide, is a highly potent and selective TrkB inhibitor without altering the binding of BDN
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