| Bioactivity | Cyclo(Arg-Gly-Asp-D-Phe-Val) is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) has antitumor activity. Cyclo(Arg-Gly-Asp-D-Phe-Val) can be used for the research of acute myeloid leukemia[1]. |
| Invitro | Cyclo(Arg-Gly-Asp-d-Phe-Val) (c(RGDfV)) (35 nM, 4-24 h) disruptes the adhesion and migration between the tumor cells and the matrix, induces the leukemia cells to leave the protective microenvironment and increases their sensitivity to cell cycle-dependent agents[1]. Cell Cycle Analysis[1] Cell Line: |
| Name | Cyclo(Arg-Gly-Asp-D-Phe-Val) |
| CAS | 137813-35-5 |
| Shortening | Cyclo(RGD-{d-Phe}-V) |
| Formula | C26H38N8O7 |
| Molar Mass | 574.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Cyclo(Arg-Gly-Asp-D-Phe-Val)
CAS: 137813-35-5 F: C26H38N8O7 W: 574.63
Cyclo(Arg-Gly-Asp-D-Phe-Val) is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) has antitumor activity. Cyclo
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