| Bioactivity | Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) has antitumor activity. Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) can be used for the research of acute myeloid leukemia[1]. | ||||||
| Invitro | Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) (c(RGDfV)) (35 nM, 4-24 h) disruptes the adhesion and migration between the tumor cells and the matrix, induces the leukemia cells to leave the protective microenvironment and increases their sensitivity to cell cycle-dependent agents[1]. Cell Cycle Analysis[1] Cell Line: | ||||||
| Name | Cyclo(Arg-Gly-Asp-D-Phe-Val) TFA | ||||||
| CAS | 199807-33-5 | ||||||
| Shortening | Cyclo(RGD-{d-Phe}-V) | ||||||
| Formula | C28H39F3N8O9 | ||||||
| Molar Mass | 688.65 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Cyclo(Arg-Gly-Asp-D-Phe-Val) TFA
CAS: 199807-33-5 F: C28H39F3N8O9 W: 688.65
Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) has antitumor act
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