| Bioactivity | Cyclizine-d3 is deuterium labeled Cyclizine. Cyclizine, a piperazine-derivative, is a potent and selective histamine H1 receptor antagonist. Cyclizine can be used for the research of nausea, vomiting, and dizziness[1][2][3][4]. |
| CAS | 1170155-67-5 |
| Formula | C18H19D3N2 |
| Molar Mass | 269.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Králová J, et, al. The effects of H1-antihistamines on the nitric oxide production by RAW 264.7 cells with respect to their lipophilicity. Int Immunopharmacol. 2009 Jul;9(7-8):990-5. [3]. Church MK, et, al. Inhibition of histamine release from human lung in vitro by antihistamines and related drugs. Br J Pharmacol. 1980 Aug;69(4):663-7. [4]. Leza JC, et, al. Effects of antihistaminics on locomotor activity in mice. Comparison with opiate and amphetamine-induced hyperactivity. Gen Pharmacol. 1991;22(2):293-6. |
Cyclizine-d3
CAS: 1170155-67-5 F: C18H19D3N2 W: 269.40
Cyclizine-d3 is deuterium labeled Cyclizine. Cyclizine, a piperazine-derivative, is a potent and selective histamine H1
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.