| Bioactivity | Cyclic MKEY is a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, which protects against atherosclerosis and aortic aneurysm formation by mediating inflammation. Cyclic MKEY also protects against stroke-induced brain injury in mice[1][2]. |
| Name | Cyclic MKEY |
| Sequence | Cys-Lys-Glu-Tyr-Phe-Tyr-Thr-Ser-Ser-Lys-Ser-Ser-Asn-Leu-Ala-Val-Val-Phe-Val-Thr-Arg-Cys (Disulfide bridge:Cys1-Cys22) |
| Shortening | CKEYFYTSSKSSNLAVVFVTRC (Disulfide bridge:Cys1-Cys22) |
| Formula | C113H174N28O34S2 |
| Molar Mass | 2530.87 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Cyclic MKEY
CAS: F: C113H174N28O34S2 W: 2530.87
Cyclic MKEY is a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, which protects against atherosc
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