| Bioactivity | Cyclacillin (Wy-4508) is an orally active aminopenicillin antibiotic, shows antibacterial activity against a wide range of gram-positive and gram-negative pathogens[1]. |
| Invitro | Cyclacillin (0-125 μg/mL) inhibits varies pathogens except Klebsiella an Enterobacter organisms with MIC values range from 0.24 μg/mL to 7.8 μg/mL[1]. |
| In Vivo | Cyclacillin (0-287 mg/kg; p.o.; single dose) shows oral activity in mice and rescues mice injected with gram-positive and gram-negative pathogens[1]. Cyclacillin (10 mg/kg; i.v.; single dose) is absorbed by the rat intestinal tissue at relatively low concentrations (less than 1 mg/mL) followed solely Michaelis-Menten kinetics[2]. |
| Name | Cyclacillin |
| CAS | 3485-14-1 |
| Formula | C15H23N3O4S |
| Molar Mass | 341.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Warren GH. Cyclacillin: microbiological and pharmacological properties and use in chemotherapy of infection - a critical appraisal. Chemotherapy. 1976;22(3-4):154-82. |
Cyclacillin
CAS: 3485-14-1 F: C15H23N3O4S W: 341.43
Cyclacillin (Wy-4508) is an orally active aminopenicillin antibiotic, shows antibacterial activity against a wide range
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