Bioactivity | Curcumin monoglucoside is a flavonoid derivative possessing antioxidant, anti-apoptotic, neuroprotective effects, and antibacterial activity. Curcumin monoglucoside can be used in research on Parkinson's disease.[1][2] |
Invitro | Curcumin monoglucoside (5 µM; 24 h) 在 N27 细胞中通过阻止 JNK 和 c-jun 的磷酸化来抑制 caspase 3 的激活,具有抗细胞凋亡作用[1]。Curcumin monoglucoside (0.25-5 µM; 24 h) 在 N27 细胞中可显著保护细胞免受 ROT (HY-B1756) (500 nM; 24 h) 诱导的神经元死亡,具有神经保护作用[1]。Curcumin monoglucoside 具有抑菌活性,对青霉素敏感、青霉素中间和青霉素耐药肺炎链球菌菌株的 MIC 值分别为 5、5、10 μg/mL[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Curcumin monoglucoside 相关抗体: |
In Vivo | Curcumin monoglucoside (500 µM) 在 ROT 果蝇模型中通过增加 GSH 水平和降低 ROS 来发挥抗氧化作用[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
CAS | 387818-26-0 |
Formula | C27H30O11 |
Molar Mass | 530.52 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Pandareesh MD, et al. Curcumin Monoglucoside Shows Improved Bioavailability and Mitigates Rotenone Induced Neurotoxicity in Cell and Drosophila Models of Parkinson's Disease. Neurochem Res. 2016 Nov;41(11):3113-3128. [2]. Li L M, et al. Antimicrobial and molecular interaction studies on derivatives of curcumin against Streptococcus pneumoniae which caused pneumonia[J]. Electronic Journal of Biotechnology, 2016, 19: 8-14. |