Curculigoside C_product_DataBase

Bioactivity	Curculigoside C is a phenolic glucoside with potent antioxidative and neuroprotective activities. Curculigoside C shows IC50 values of 0.25 mM and 0.88 mM for hydroxyl radicals and superoxide anion radicals, respectively[1].
Invitro	Curculigoside C 在评估 H2O2[2] 诱导的 SY5Y 细胞死亡中具有神经保护作用。
In Vivo	Curculigoside C (15、30 和 60 mg/kg) 表现出快速的口服吸收（Tmax = 0.106 h、0.111 h 和 0.111 h），高消除（t1/2 = 2.022 h、2.061 h 和 2.048 ）和低绝对生物利用度（分别为 2.01%、2.13% 和 2.39%）[2]。大鼠血浆中 Curculigoside C (CC) 灌胃后的药代动力学参数[1]。
Name	Curculigoside C
CAS	851713-74-1
Formula	C22H26O12
Molar Mass	482.43
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Wu Q, et al. Antioxidative phenols and phenolic glycosides from Curculigo orchioides. Chem Pharm Bull (Tokyo). 2005 Aug;53(8):1065-7. [2]. Di Wu, et al. Pharmacokinetic and Metabolism Studies of Curculigoside C by UPLC-MS/MS and UPLC-QTOF-MS. Molecules. 2018 Dec 21;24(1):21.

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