Bioactivity | Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP[1]. Crustecdysone exhibits regulatory or protective roles in the cardiovascular system[2]. Crustecdysone is an active metabolite of Ecdysone (HY-N0179)[3]. |
Invitro | Crustecdysone 在果蝇重塑脂肪体过程中诱导细胞自噬和 caspase-3 活性[1]。 |
Name | Crustecdysone |
CAS | 5289-74-7 |
Formula | C27H44O7 |
Molar Mass | 480.63 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |