| Bioactivity | Crolibulin (EPC2407) is a tubulin polymerization inhibitor, with potent apoptosis induction and cell growth inhibition. Crolibulin has anti-tumor activity. Crolibulin also has cardiovascular toxicity and neurotoxicity[1][2][3]. | ||||||||||||
| Invitro | Crolibulin shows significant cytotoxic activity against HT-29 cells, with an IC50 of 0.52 μM[2].Crolibulin is active against various experimental tumors and exhibit potent inhibition of mitosis at the G2/M stage[2]. | ||||||||||||
| Name | Crolibulin | ||||||||||||
| CAS | 1000852-17-4 | ||||||||||||
| Formula | C18H17BrN4O3 | ||||||||||||
| Molar Mass | 417.26 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Crolibulin
CAS: 1000852-17-4 F: C18H17BrN4O3 W: 417.26
Crolibulin (EPC2407) is a tubulin polymerization inhibitor, with potent apoptosis induction and cell growth inhibition.
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