Bioactivity | Cremophor EL-36 (Polyoxyethylene(36) Castor Oil; PEG-36 Castor Oil) is a commonly used solvent that can be used to prepare paclitaxel solutions after being mixed with ethanol[1][2]. |
CAS | 61791-12-6 |
Appearance | 粘稠液体 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
Reference | [1]. Sparreboom A, et al. Nonlinear pharmacokinetics of paclitaxel in mice results from the pharmaceutical vehicle Cremophor EL[J]. Cancer research, 1996, 56(9): 2112-2115. [2]. Szebeni J, et al. Complement activation by Cremophor EL as a possible contributor to hypersensitivity to paclitaxel: an in vitro study[J]. JNCI: Journal of the National Cancer Institute, 1998, 90(4): 300-306. |