| Bioactivity | Coumarin-d6 is deuterated labeled trans-2-Undecenal (HY-W127505). Trans-2-UndecenalIt is an organic compound belonging to aldehydes. It has a strong, pungent smell and is commonly found in a variety of foods, including fruits and vegetables. Trans-2-UndecenalIt has a variety of applications in the flavor and fragrance industry, especially as a fragrance agent in products such as perfume, cologne and air fresheners. In addition, it can also be used as an intermediate in the synthesis of various chemicals and drugs. |
| Invitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Coumarin-d6 相关抗体: |
| In Vivo | Coumarin (1-10 mg/kg; p.o.) shows an antinociceptive effect in a dose-dependent manner in the acetic acid-induced writhing test[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| CAS | 116295-83-1 |
| Formula | C9D6O2 |
| Molar Mass | 152.18 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Park SH, et al. Antinociceptive profiles and mechanisms of orally administered coumarin in mice. Biol Pharm Bull. 2013;36(6):925-30. [3]. enugopala KN, et al. Review on natural coumarin lead compounds for their pharmacological activity. Biomed Res Int. 2013;2013:963248. |