| Bioactivity | Cot inhibitor-3 (Compound 33) is a potent, selective cancer osaka thyroid (COT) kinase inhibitor, with an IC50 of 4 nM. Cot inhibitor-3 can be used to prevent inflammation-driven lameness[1]. |
| Target | IC50: 4 nM (cancer osaka thyroid) |
| CAS | 1984784-12-4 |
| Formula | C30H28N8O |
| Molar Mass | 516.60 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Glatthar R, et, al. Discovery of Imidazoquinolines as a Novel Class of Potent, Selective, and in Vivo Efficacious Cancer Osaka Thyroid (COT) Kinase Inhibitors. J Med Chem. 2016 Aug 25;59(16):7544-60. |
Cot inhibitor-3
CAS: 1984784-12-4 F: C30H28N8O W: 516.60
Cot inhibitor-3 (Compound 33) is a potent, selective cancer osaka thyroid (COT) kinase inhibitor, with an IC50 of 4 nM.
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