| Bioactivity | Corynoxine B is an oxindole alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese); a Beclin-1-dependent autophagy inducer. IC50 value:Target: Autophagy inducerin vitro: Corynoxine B, a natural autophagy inducer, restores the deficient cytosolic translocation of HMGB1 and autophagy in cells overexpressing SNCA, which may be attributed to its ability to block SNCA-HMGB1 interaction [1].in vivo: Corynoxine B exhibited prolongation of the thiopental-induced hypnosis on oral administration in mice [2]. | ||||||||||||
| Name | Corynoxine B | ||||||||||||
| CAS | 17391-18-3 | ||||||||||||
| Formula | C22H28N2O4 | ||||||||||||
| Molar Mass | 384.47 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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Corynoxine B
CAS: 17391-18-3 F: C22H28N2O4 W: 384.47
Corynoxine B is an oxindole alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese); a Beclin-1-d
Data collection：peptidedb@qq.com
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