| Bioactivity | Cortagine is a specific corticotropin-releasing factor receptor subtype 1 (CRF1) agonist with an IC50 of 2.6 nM for rCRF1. Cortagine is an anxiolytic and antidepressive drug in the mouse model[1]. | ||||||
| Invitro | Cortagine inhibits rCRF1 (EC50=0.18 nM) and mCRF2β (EC50=16 nM) in transfected HEK-293 cells[1]. | ||||||
| Name | Cortagine | ||||||
| Formula | C192H323N55O63S | ||||||
| Molar Mass | 4442.06 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |