| Bioactivity | Concanamycin B is a macrolide antibiotic, which can inhibit the cavitation type H+-ATPases, and the IC50 value is 5 nM[1]. |
| Invitro | Concanamycin B (5-25 nM, 1h) 可抑制氧化低密度脂蛋白诱导的巨噬细胞 J774 中脂滴和胆固醇酯的积累[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Concanamycin B 相关抗体: |
| CAS | 81552-33-2 |
| Formula | C44H71NO14 |
| Molar Mass | 838.03 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yilla M, et al. Involvement of the vacuolar H(+)-ATPases in the secretory pathway of HepG2 cells. J Biol Chem. 1993 Sep 5;268(25):19092-100. PMID: 8395529. [2]. Woo JT, et al. Inhibition of the acidification of endosomes and lysosomes by the antibiotic concanamycin B in macrophage J774. Eur J Biochem. 1992 Jul 1;207(1):383-9. |
Concanamycin B
CAS: 81552-33-2 F: C44H71NO14 W: 838.03
Concanamycin B is a macrolide antibiotic, which can inhibit the cavitation type H+-ATPases, and the IC50 value is 5 nM.
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This product is for research use only, not for human use. We do not sell to patients.